IB-PRO™ 40MG

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1 5
30 CAPSULES

IB-PRO™ 40MG

IB-PRO™ 40MG

Supports normal bowel movements, occasional bloating & digestive upset †

  • World-first formulation of Unique IS-2™️ and Lactospore® probiotic strains
  • IB-PRO™️ offers all the bowel movement & digestive health benefits of IB-ONE™️†
  • Plus additional support for occasional bloating, gas, indigestion & digestive upset†
  • A duobiotic with 2 clinically studied strains in 1 - View studies
  • Just 1 capsule per day - contains 4b CFUs / 40mg
  • Designed for sensitive guts - low FODMAP, gluten free & non-GMO
  • 3rd party tested for allergens, heavy metals & contaminants - View results
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Material
Clinical Studies
Supplement facts
  • Low FODMAP
  • GMO free
  • Gluten free
  • Dairy free
  • Soy free

HOW TO TAKE

Take 1 capsule per day.

IB-PRO™ contains 2 strains that can survive stomach acid and can be taken with or without food, at any time of day.

Shelf stable: No refrigeration required.

PACKAGING

IB-PRO™ comes in protective foil blister packaging to ensure the probiotics remain potent. Each box contains three blisters, each with 10 capsules, for a total of 30 capsules. The blisters are housed in a recyclable cardboard box, making it easy to store and environmentally friendly.

INGREDIENTS

Active Ingredient: Bacillus coagulans Unique IS-2™ (MTCC 5260, ATCC PTA-11748): 2 Billion CFU (20 mg); Bacillus coagulans LactoSpore® (MTCC 5856): 2 Billion CFU (20 mg)**

Other Ingredients: Microcrystalline Cellulose, Vegetarian Capsule (Cellulose, Water), Vegetable Stearate, Silicon Dioxide

**Daily Value (DV) not established.

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  • Clinical Studies

    The effects of Bacillus coagulans MTCC 5856 on functional gas and bloating in adults: A randomized, double-blind, placebo-controlled study

    Background: Gut microbiome dysbiosis is a major cause of abdominal gas, bloating, and distension. Bacillus coagulans MTCC 5856 (LactoSpore) is a spore-forming, thermostable, lactic acid-producing probiotic that has numerous health benefits. We evaluated the effect of Lacto Spore on improving the clinical symptoms of functional gas and bloating in healthy adults.

    Methods: Multicenter, randomized, double-blind, placebo-controlled study at hospitals in southern India. Seventy adults with functional gas and bloating with a gastrointestinal symptom rating scale (GSRS) indigestion score ≥ 5 were randomized to receive B coagulans MTCC 5856 (2 billion spores/day, N = 35) or placebo (N = 35) for 4 weeks. Changes in the GSRS-Indigestion subscale score for gas and bloating and global evaluation of patient's scores from screening to the final visit were the primary outcomes. The secondary outcomes were Bristol stool analysis, brain fog questionnaire, changes in other GSRS subscales, and safety.

    Results: Two participants from each group withdrew from the study and 66 participants (n = 33 in each group) completed the study. The GSRS indigestion scores changed significantly (P < .001) in the probiotic group (8.91-3.06; P < .001) compared to the placebo (9.42-8.43; P = .11). The median global evaluation of patient's scores was significantly better (P < .001) in the probiotic group (3.0-9.0) than in the placebo group (3.0-4.0) at the end of the study. The cumulative GSRS score, excluding the indigestion subscale, decreased from 27.82 to 4.42% (P < .001) in the probiotic group and 29.12 to 19.33% (P < .001) in the placebo group. The Bristol stool type improved to normal in both the groups. No adverse events or significant changes were observed in clinical parameters throughout the trial period.

    Conclusions: Bacillus coagulans MTCC 5856 may be a potential supplement to reduce gastrointestinal symptoms in adults with abdominal gas and distension.

    View study (PubMed)

    Majeed M, Nagabhushanam K, Paulose S, Arumugam S, Mundkur L. The effects of Bacillus coagulans MTCC 5856 on functional gas and bloating in adults: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2023 Mar 3;102(9):e33109. doi: 10.1097/MD.0000000000033109. PMID: 36862903; PMCID: PMC9982755.

  • Clinical Studies
  • Supplement Facts

    Other Ingredients: Microcrystalline Cellulose, Vegetarian Capsule (Cellulose, Water), Vegetable Stearate, Silicon Dioxide

Our Most Advanced Probiotic

Results from clinical studies using Unique IS-2™️ & Lactospore® show:

Support Normal Bowel Movements†

"In the present investigation, we have shown that B. coagulans Unique IS2 (2 billion CFU) significantly improved the number of bowel movements per week..."

- Madempudi et al, J. Probiotics. Ant. Pro. 2020; PubMed ID: 30911991

Promote Healthy Digestion†

"...other GSRS ratings (reflux, constipation, and stomach [discomfort]) improved by 84.1% [in Lactospore®] compared to 33.65% in the placebo group."

- Majeed et al, Med.® 2023; PubMed ID: 36862903

Relief From Bloating & Gas†

"B coagulans MTCC5856 showed promising results by dramatically lowering gas, bloating, and flatus related symptoms in patients..."

- Majeed et al, Med.® 2023; PubMed ID: 36862903

Relief From Digestive Upset†

"...the indigestion [also called dyspepsia or an upset stomach] scores fell by 65.5% in the B coagulans MTCC5856 group compared to 11.5% in the control group".

- Majeed et al, Med.® 2023; PubMed ID: 36862903

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Clinically Studied Probiotics

A world-first blend of 2 outstanding probiotics for gastrointestinal support†

Unique IS-2™️
Unique IS-2™️ MTCC 5260, ATCC PTA-11748, is a Bacillus coagulans probiotic strain that has been extensively studied in over 20 human clinical trials, including 8 specifically focused on digestive health. These clinical studies have been conducted between 2011 and present, with more trials planned. This ongoing research highlights the strain's remarkable efficacy and safety profile.
Lactospore®
LactoSpore® MTCC 5856 is another highly researched probiotic strain from the Bacillus coagulans family. Like Unique IS-2™, it has undergone numerous human clinical trials. Notably, 4 of these trials have focused on gut health and were conducted to the highest standards as randomized, double-blind, placebo-controlled studies. Recent studies have shown LactoSpore® to be particularly effective for reducing occasional bloating and gas, a benefit that complements the strengths of Unique IS-2™. This makes LactoSpore® an excellent companion strain to Unique IS-2™, offering a broader range of digestive support.






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The Details Matter

No unnecessary fillers
Formulated without gluten, dairy & soy
Vegetable capsules free of animal products
Shelf stable convenience - no refrigeration required
Blister packaging to protect from light, moisture & oxygen
Capsules that release active ingredients in the GI tract - where they are needed
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8 Week Satisfaction Program

Experience IB-PRO™ Risk-Free

In clinical studies using these probiotic strains, participants experienced benefits within 2 weeks, with most improvements by week 4 onwards. To give you enough time to see how IB-PRO™ works for you, we offer a no-questions-asked 8 Week Satisfaction Program. If you're not completely satisfied, simply return it for a full refund.

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Frequently Asked Questions

You can take IB-PRO™ any time of day. For optimal results, try to take it at the same time each day.

Some probiotic companies advise taking their products with a meal to ensure the best survival rate through the body's gastric acidity. Others suggest taking them on an empty stomach to limit exposure to digestive enzymes and bile.

However, IB-PRO™ is a spore-forming probiotic, naturally resistant to stomach acid and intestinal factors. This flexibility means you can take it at any time of day that fits your routine, without worrying about its effectiveness.

You can take IB-PRO™ with or without food.

While other probiotic companies advise taking their products with a meal to ensure the best survival rate through gastric acidity, while others suggest an empty stomach to avoid digestive enzymes and bile.

With IB-PRO™, timing isn’t an issue. As a spore-forming probiotic, it is naturally resistant to stomach acid and intestinal factors. This means you can take it with or without food, at any time of day that fits your routine, without compromising its effectiveness. Whether with breakfast, lunch, dinner, or on an empty stomach, IB-PRO™ easily fits into your daily routine.

Yes, you can.

IB-PRO™ is a spore-forming probiotic, naturally resistant to stomach acid. Unlike other probiotics that need special coatings (i.e. enteric / delayed release capsules) to survive gastric acid and must remain in the capsule when taken, IB-PRO™ can be opened and mixed with your food or drink without losing effectiveness. While the capsules are easy to swallow, you have the flexibility to take it in whatever way is most convenient for you.

Yes, IB-PRO™ is suitable for most diets and dietary restrictions.

IB-PRO™ is free from common allergens and contains no animal-derived ingredients, making it vegetarian-friendly. It is also independently tested by third parties for gluten, dairy (including milk and casein) and soy, to ensure it meets the highest standards.

IB-PRO™ is suitable for a variety of diets, including Low FODMAP, Vegan, Vegetarian, Ketogenic, Gluten-Free, Paleo, Mediterranean, and more. This versatility makes IB-PRO™ an inclusive option for supporting your gut health, no matter your dietary needs.

No, IB-PRO™ does not need to be refrigerated.

Our spore-forming probiotic is designed to be shelf-stable at room temperature, maintaining its potency without the need for refrigeration.

This makes it convenient for you to take your probiotics with you wherever you go.

In clinical studies using these strains, participants began to notice symptom support from day 15 (week 3) onwards.

This means you might start to experience the effects after 2 weeks of daily use, with the most significant benefits typically becoming evident after 4 weeks of consistent use.

Madempudi et al. 2020 - Unique IS-2™️ MTCC 5260

Majeed et al. 2023 - Lactospore® MTCC 5856

To give you enough time to see how MIOME works for you, we offer a no-questions-asked 8 Week Satisfaction Program. If you're not completely satisfied, simply return your product for a full refund.

We are planning to expand our international shipping options later this year. In the meantime, you can access our products using a mail forwarding service like MyUS.com. MyUS offers extremely competitive international shipping rates and is very easy to use.

Simply sign up for an account, and they will provide you with a U.S. address to use for your Miome orders. Once your order arrives at their facility, MyUS will forward it to your international address.

This way, you can enjoy our products no matter where you are.